ABSTRACT
Objective: The objective of the study was to measure the frequency of impaired glucose tolerance [IGT] in patients having chronic hepatitis C at medical outpatient department [OPD] of Allied hospital Faisalabad
Sample technique: Non probability consecutive sampling
Duration of study: Duration of study was 6 months with first patient enrolled on 3.02.2010 and last patient enrolled on 07-08-2010
Setting: Medical [OPD] Outpatient Department of Allied Hospital, Faisalabad
Subjects: 375 patients with chronic hepatitis C, coming in Medical OPD of Allied hospital Faisalabad were enrolled
Methods: 375 patients diagnosed as having chronic hepatitis C coming in Medical OPD of Allied hospital Faisalabad, were included in the study. Fasting and two hours after glucose load blood sample were collected in sterilized syringes and was tested for fasting blood glucose [FBS] and random blood glucose level [RBS]
Results: In this study 375 patients having HCV positive on Elisa were enrolled. Out of 375 patients with chronic hepatitis C, 143 [38.1%] were found to have IGT while 232 [61.9%] were having no IGT. There was significant association between chronic hepatitis C and development of IGT
Conclusions: It is concluded that there is close association in the development of IGT in patients with chronic hepatitis C
ABSTRACT
Magnesium is the fourth most abundant cation in the body and the second most abundant intracellular cation after potassium. Magnesium plays a fundamental role in many functions of the cell, including energy transfer, storage, and uses protein, carbohydrate, and fat metabolism; maintenance of normal cell membrane function; and the regulation of parathyroid hormone [PTH] secretion. To determine the frequency of hypomagnesaemia in patients presenting with acute coronary syndrome [ACS]. Cross -sectional study. Coronary Care Units and medical ward in Allied Hospital Faisalabad, from 26-01-2010 to 25-07-2010. The study was conducted in medical unit II and coronary care unit of Allied Hospital Faisalabad. Sample Size: Sample size was calculated by using WHO sample size calculator taking confidence level 95%, population proportion 7.7% and required precision 4%. Sample size n = 171. Non-probability consecutive sampling. A total of 171 patients fulfilling the criteria of ACS admitted in M-ll and CCU were enrolled in the study, demographic details, history and clinical examination of the patients were recorded. Blood sample was collected in estimation of serum magnesium level. In this study the mean serum magnesium was 1.59 +/- 8.380 in males and 1.56 +/- 7.678 in females. Among the 171 acute coronary syndrome patients, 14 [8.2%] were diagnosed with hypomagnesaemia. There were 8 [8.8%] male and 6 [7.5%] female patients. 157 [91.8%] patients did not have hypomagnesaemia out of 83 [91.2%] were male and 74 [92.5%] were female patients. There was male predominance. Male to male ratio was 1.33:1. The results showed that frequency of hypomagnesaemia in acute coronary syndrome was significantly high and comparable to other studies. There was male preponderance. However, there was variation in the occurrence of hypomagnesaemia in acute coronary syndrome. Early assessment of serum magnesium concentration is needed in acute coronary syndrome in order to implement proper magnesium supplementation
Subject(s)
Humans , Male , Female , Magnesium/blood , Cross-Sectional StudiesABSTRACT
To determine the frequency of microalbuminuria in patients with ischemic stroke. This cross-sectional study was conducted from 1[st] April 2009 to 30[th] September 2009 at Allied Hospital, Faisalabad. 195 patients of ischemic stroke, with or without diabetes mellitus and hypertension were tested for early morning urine albumin to creatinine ratio. A urinary albumin to creatinine ratio of 30 to 300 micro g/mg was considered as microalbuminuria. Out of 195 patients, microalbuminuria was present in 94 [48.2%] patients. Out of 68 diabetic patients, microalbuminuria was present in 37 [54.4%] patients while out of 127 non- diabetics, 57 [44.9%] had microalbuminuria. Out of 113 hypertensive patients, microalbuminuria was present in 56 [49.6%] while out of 82 non hypertensives, 38 [46.3%] had microalbuminuria. Among 28 patients having both diabetes mellitus and hypertension, 16 [57.1%] had microalbuminuria. Out of 42 patients without both diabetes and hypertension, 17 [40.5%] had microalbuminuria. We found high frequency of microalbuminuria in patients with ischemic stroke. Therefore, microalbuminuria could be is a useful modifiable factor, in addition to conventional risk factors, in identifying those at increased risk of ischemic stroke